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Robert H. Lurie Comprehensive Cancer Center of Northwestern University
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Repository: Gynecology Oncology Biospecimen Bank

General

Principle Investigator(s): Jian-Jun Wei, MD & Shohreh Shahabi, MD

Manager: Saurabh Malpani s-malpani@northwestern.edu

IRB Protocol Name: NU 00X3: Pathology Core Facility – Gynecology & Oncology

IRB Protocol Number: STU00020989

Description:

The aim of the Gynecology Oncology Biospecimen Repository is to establish a resource for human biospecimens. A main mission of the repository is to consent patients prior to surgery diagnosed with ovarian or endometrial cancer and then procure and process tissue and blood samples for researchers, while maintaining patient confidentiality.

Access to the biospecimen repository will foster collaborations between clinicians and scientists that will facilitate the rapid identification of a set of molecular, biochemical, functional, and genetic markers, which can be employed to effectively detect and manage ovarian cancer and other gynecological malignancies.

 

IRB Process: IRB approval or exemption must be obtained prior to release of data or specimens. The request form will ask you to input your IRB number or declare your IRB exemption.

Scientific Justification: The request form will ask you to attach a 'Methods/Justifications' document that should contain a scientific explanation justifying the disbursement of the clinical data and/or clinical specimens.

 

Specimen

 

Type

Organ

Blood

Endometrium – 36

Ovary - 18

*Tissue

(frozen or fresh)

Endometrium – 33

Ovary - 17

*Does not include slides or blocks

 

As of 6/27/17

 

Subjects

Total Samples

Blood - Plasma

56

107

Blood-Serum

55

171

Blood – Buffy+RBC

56

56

Fresh Tissue

3

6

Frozen Tissue (unspecified tumor)

37

68

Frozen Tissue (normal)

40

67

*Stained Slide

50

86

*Tissue FPE Block

50

86

Whole Blood

55

109

*Normal and/or tumor

 

 

Data
Race Ovary Endometrium
White 17 30
Black 1 8
Native Hawaiian or Other Pacific Islander 0 0
Asian 2 2
American Indian or Alaska Native 0 0
Unknown 2 5
More than one race 0 0
Hispanic 1 3

 

Summary of categories of the data points collected:

  • Demographics
  • Family History
  • Comorbidities
  • Diagnosis
  • Treatment
  • Followup
  • Survival